Ways of knowing and ways of doing are being deeply impacted by digital technology from the perspective of individuals, institutions, societies, and global communities. The way in which we view ourselves and create images of self are mirrored through visual culture, expressed through and influenced by digital communication and knowledge transfer. Cultural informatics studies this dynamic state of cultural transformation on both the macro and micro levels. For information professionals and scientists, this means research in human computer interaction, information design and interaction, technology in education and learning, and the conveyance of meaning through digital media. As cultural heritage is digitized at increasing rates and is made widely accessible, the past converges, or perhaps collides, with the present, causing unprecedented juxtapositions of diverse cultures in a sea of mass communication and across an unbounded digital universe.