Michele Pasin / Quotes

Knowledge discovery in escience

Each Knowlet has an ‘attraction’ to each other Knowlet with similar concepts in its ‘Object Cloud’, while some knowlets have very little to do with each other and may even repulse each other, some others may move closer and close in the Concept Web, pushed and pulled by many other knowlets in the space. The Knowlet of Malaria may move so close to the Knowlets of the cancer drug Tegafur that, even though they have never been mentioned together before, the Social Machine will hypothesise a potential anti-malaria role for the drug. [...] eScience needs different complementary levels of reasoning. Think of the metaphor of the helicopter view. One would never see the abbarent growth pattern in a cornfield caused by the remains of a Roman fortress when walking in the midst of the field. However, after spotting the pattern from the helicopter, one needs to land, take a shovel and dig to find the ruines. Next step would be the laboratory experiments to demonstrate the age of the stones before the conclusion can be drawn that indeed the pattern observed revealed a Roman fortress. Knowlets enable the helicopter view. With for instance Description Logics the immediate surroundings of the new associations can be explored (compared to the shovel), whilst final comfirmation of causal biological relationships in the wet Lab will follow.

Saved 2 July 2013 / www.lumc.nl ↗

#malaria #patterns #drugs #age #association

Bacteria as honorable foes that prune mankind

For the enemy/friends of man are his pruners. They prevent him from destroying himself by excess fertility, so that a person who dies of malaria or…

The Book: On The Taboo Against Knowing Who You Are #malaria #penicillin #men #persons #rest

A beauty that sours without goodness

It was impossible for me to tell her age or her nationality. She might’ve been Spanish. She might’ve been Russian. She might’ve been Indian, in part, or…

Shantaram (gregory David Roberts) #age #eyes #heart

Middle-aged women disappear

A second, related way in which the social self matters is that if people are treated very differently depending on how they appear, that can change how they…

The Ego Trick (baggini, Julian) #society #women #age #self

Ripples of meaning around us

Even though it seemed a little New Age-y for the Silicon Valley set (yeah, right), I started wearing an interesting blue medallion around that I found because…

The Daily Portal – Jon Mitchell, Cosmos Journalist #age #portal #persons #interviews

Same stages, different ages

Piaget believed that children all pass through the same stages when developing their thinking skills. The age at which children accomplish these stages of…

Theories of Childhood, Second Edition (Carol Garhart Mooney) #child-development #thinking #age

The Saturn Return

FOR ASTROLOGY THERE ARE two particularly critical junctures in the life of any individual, the first at the end of their twenties, and the second at the end…

The Acid Diaries (Christopher Gray) #astrology #age #self